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Register for our upcoming webinar on ultrasensitive detection and quantification of CNVs and mutations.
New Publication –
Calibration-free NGS quantitation of mutations below 0.01% VAF. Read More
Introducing the VarTrace® MSI qPCR Assay. Learn More
Introducing our Product Proof of Concept Program. Learn More
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The only liquid biopsy panel to detect 0.1% VAF requiring only 1 million NGS reads
The VarMap Pan-Cancer NGS Panel enables highly sensitive variant detection and quantitation across hundreds of loci in 61 genes. Utilizing BDA technology and next-generation sequencing, the VarMap Pan-Cancer panel significantly improves the limit of detection (≥0.1% VAF) while reducing the number of reads required. The panel is compatible with several sample types, including cell-free DNA, tumor sections, and PBMC DNA.
Accurately detect SNVs and indels in 14 genes and CNVs across 18 genes associated with breast cancer
The CNV+ Breast Cancer NGS Panel covers 84 frequently mutated breast cancer hotspots in 14 genes and CNVs of 18 genes including HER2. Using QASeq technology, the CNV+ Breast Cancer NGS Panel accurately quantifies SNVs and indels down to 0.2% VAF and detects CNVs in HER2 at 2.04/1.97 single heterozygous copy gain/loss from cfDNA or tumor tissue.
Highly sensitive detection of microsatellite instability in five MSI loci using qPCR.
NuProbe’s VarTrace MSI Assay enables detection of MSI-high (MSI-H) status with a limit of detection down to 1% in five mononucleotide markers (BAT-25, BAT-26, NR-21, NR-24, and MONO-27).
qPCR/Sanger assays to identify variants down to 0.1% VAF
Custom solutions for your biomarker needs
The Augury Biopharma Services leverage our proprietary technologies to create optimal solutions for your process, across test modalities such as next-generation sequencing (NGS) and qPCR. The flexibility of our platform facilitates the design of custom solutions across numerous diseases and applications.
At NuProbe, we are developing innovative assays to accelerate cancer research. Our products allow laboratories to detect and quantify low-abundant variants across multiple platforms from both cell-free DNA and tissue specimens. Contact us today to learn more.
We provide assay development and testing services to support all stages of biomarker detection programs. Our flexible platform utilizes proprietary technologies to deliver best-in-class sensitivity from solid tumor and liquid biopsy. Contact one of our experts today to find out what NuProbe can do for you.
Stay in touch for the latest NuProbe developments
By integrating molecular barcoding technology with the Blocker Displacement Amplification (BDA) allele enrichment, the team invented the new quantitative BDA (QBDA) method that overcomes potential biases in BDA to enable accurate VAF quantitation.
The deal will combine C2i’s AI-driven cancer intelligence platform with NuProbe’s advanced sequencing technology to power pharma and diagnostic services.
OCEANS enables rapid, accurate, and affordable detection of somatic mutations as low as 0.05% VAF. This novel research will facilitate the development of same-day, low-cost oncology panels for time-sensitive therapy selection and recurrence monitoring.
NuProbe will integrate QASeq and BDA technologies with Bionano’s Saphyr system for research and product development in the fields of reproductive health and oncology liquid biopsies.
NuProbe published research on DNA microsatellites in Nucleic Acids Research and released VarTrace® MSI qPCR research use only assay.
Dec 11-14, 2021
Jan 26-28, 2022
Feb 10-11, 2022
Liquid Biopsy for Precision Oncology Summit
Feb 21-23, 2022
Molecular & Precision Med Tri-con
Apr 8-13, 2022
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Rare allele enrichment technology by PCR that enables the selective amplification and detection of low-abundant sequence variants down to 0.01% variant allele frequency (VAF).
NGS-based method that utilizes unique molecular identifiers (UMIs) and highly multiplexed partially nested PCR primer design to detect mutations and copy number variations with high sensitivity.
