Augury Custom NGS Panels

Rapid Development

Sensitive Mutation, Indel, and CNV Detection

Low Input DNA

Gene Selection and Coverage options

VarMap: NGS

Features

Affordable

Only 1 million reads for liquid biopsy

Ultrasensitive

Limit of detection down to 0.1% VAF

Quantitative

>95% VAF quantitation accuracy

Sample Flexibility

Compatible with several sample types

Sample Data

VarMap NGS Panels preferentially amplify variant molecules, resulting in a reduction of required sequencing reads by 60-fold compared to deep sequencing approaches.

Products

VarMap™ Pan-Cancer NGS Panel

Detects over 6300 COSMIC mutations in over 60 genes

CNV+: NGS

Features

Ultrasensitive

Limit of detection down to 0.1% VAF

Quantitative

>95% VAF quantitation accuracy

Quick Turnaround Time

6-hour DNA-to-Library workflow

Sample Flexibility

Compatible with several sample types

Sample Data

CNV+ panels use QASeq technology, which is more sensitive than ddPCR. The panels detect deletions and mutations, that can not be done with IHC. QASeq technology allows analyzing thousands of loci, while ddPCR analyzes 1 locus.

Products

CNV+ Breast Cancer NGS Panel 

Detects 84 mutation hotspots in 14 genes and detect ERBB2 Copy Number Variations (CNVs) in a single reaction

VarTrace®: qPCR, Sanger

Features

Ultrasensitive

Limit of detection down to 0.1% VAF

Comprehensive

Detects up to 500 COSMIC mutations

Quantitative

Accurate quantitation

Sample Flexibility

Compatible with several sample types

Sample Data

BRAF mutation testing

NuProbe’s BDA technology enriches the variant allele frequency (VAF) of mutations by over 200-fold, improving Sanger’s limit of detection of 20% VAF to 0.1% VAF.

Products

VarTrace® AML Panel

Detects 254 AML hotspot mutations in FLT3, DNMT3A, IDH1, IDH2, KIT, NPM1 genes

VarTrace® EGFR Assay

Detects 400 mutations in exons 18, 19, 20, and 21 in FFPE and plasma samples

VarTrace® BRAF Assay

Detects mutations in codons 596–601 in FFPE and plasma samples

Customized qPCR/Sanger Assays and Services

Features

Customizable

Automatically design custom BDA assays

Rapid Turnaround

2-3 days

Ultrasensitive

Limit of detection down to 0.1% VAF

Sample Data

NGSure’s proprietary algorithm designs custom BDA assays with a limit of detection of 0.1% VAF, significantly expanding the range of mutations detected by NGS.

News & Press Releases

NuProbe Launches Liquid Biopsy Pan-Cancer NGS Panel

By All News, Products

The VarMap Pan-Cancer NGS Panel uses the quantitative blocker displacement amplification technology to enrich, detect, and quantitate over 6500 mutations and indels in 61 clinically relevant genes. The panel can be used on cfDNA samples to detect mutations down to 0.1% variant allele frequency (VAF) using only 1 million NGS reads. The panel can also be applied to FFPE tumor samples or other cellular samples for minimum residual disease (MRD) detection, detecting mutations down to 0.01% VAF.

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NuProbe and Weigao Group Form Strategic Collaboration to Develop Liquid Biopsy Panel

By All News, Strategic Collaborations

NuProbe and Weigao Group will apply NuProbe’s proprietary Blocker Displacement Amplification (BDA) technology to developing a liquid biopsy NGS panel for non-small cell lung cancer (NSCLC). The product will be compatible with the desktop NGS instruments, and the companies plan to later apply for in vitro diagnostic (IVD) registration with NMPA, China’s equivalent of FDA.

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NuProbe Licensed Two Technologies from Rice University, Launched Nanopore AML multi-gene panel

By All News, Products

The first, Non-Extensible Oligonucleotides (NEO), will allow NuProbe to provide much more rapid development of customized NGS panels, with turnaround time of less than 4 weeks. The second, Linear DNA Assembly (LDA) technology, improves the effective throughput of nanopore sequencing by up to 10-fold for short DNA, such as DNA extracted from FFPE tumor tissues and cell-free DNA from peripheral blood. Concurrently, NuProbe announces the launch of its new VarMap™ Nanopore product line.

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May 17-21, 2021
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June 09–12, 2021
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June 12–15, 2021
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