NuProbe’s Augury Custom NGS platform is designed to build the customized diagnostic solutions your biopharmaceutical company needs. Let us know your target biomarkers by contacting our scientists, or try Augury™, our easy-to-use custom panel builder tool. Panels can be built to cover either full exons or hotspot regions and detect copy number variants, insertions and deletions, single nucleotide variants, and microsatellite instability (MSI).
NuProbe is with you from discovery to commercialization. Our design algorithm will construct the initial panel, which is then evaluated for feasibility by our scientists. Full support of our dedicated R&D staff is provided throughout the process of optimization and validation of your panel, ensuring that the final product delivers the results you need. Use Augury™, our Custom NGS Panel Builder below to get started — or contact our scientists for questions or assistance.
Our platform utilizes our proprietary quantitative amplicon sequencing (QASeq) technology to detect mutations down to 0.2% VAF and copy number variants at 1.94/2.06 ploidy using small amounts of input DNA. QASeq utilizes unique molecular identifiers (UMIs) and PCR to accurately quantify these genetic variants. NuProbe’s chemistry has a high conversion yield (median >60%), allowing sensitive detection from small specimen inputs (30ng FFPE DNA, 8ng fresh/frozen DNA, 10ng cfDNA).
3 Easy Steps
- 1 Select genes
- 2 Review panel specifications
- 3 Submit for quote